Porphyric neuropathy in black South Africans: a case series

Abstract Porphyria is a rare disorder that results from mutations in the genes important haem biosynthesis. Several types are described. Acute attacks lead to central, autonomic and peripheral nervous system manifestations. These acute typically occur intermittent porphyria, less so variegate porphyria. The neuropathy this condition can mimic Guillain-Barré syndrome (GBS), often misdiagnosed incorrectly treated. It general, but considered be extremely uncommon black African population. We describe five South patients, three of whom were diagnosed with presenting manifestation severe neuropathy. was atypical nature variable presentation highlight importance considering porphyria such patients.